Athrombocytopenic thrombotic microangiopathy: diagnosis not performed with the present criteria
Abstract
The disease category of thrombotic microangiopathy (TM) encompass different entities such as thrombocvtopenic thrombotic purpura (TTP) and uremic hemolytic syndrome (UHS), both strongly related and whose diagnosis relies on the presence of non immune hemolytic anemia and trombocytopenia, findings that should urge the caring physician to start plasmapheresis promptly. We report the case of a 51 year old woman admitted with acute-subacute renal failure of unknown etiology whose renal biopsy finding was thrombotic microangiopathy, in absence of thrombocytopenia and haemolytic anemia. This inusual case and according to published literature can not be diagnosed on standard accepted criteria and others markers like ADAMTS-13 should be considered.
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