Dialysis dose in chronic patients provided with Genius System (G)

Abstract

Dialysis dose is an important parameter for dialysis adequacy, the quantification by Kt/V in G batch system could be limited because dialysate flow (Qd ml’) x time in minutes cannot exceed bottle contain volume (85 or 90 liters). Our objective was to establish if patients treated with G system reach the minimum adequate dose (Kt/V sp: 1.20 o URR: 65%); or the target dose (Kt/Vsp 1.40 ó URR 70 %) according to K-DOQI Guidelines 2006 and minimum adequate dialysis dose (Kt/Ve > = 1.20) according to European Guidelines (EBPG) 2007. The data from 76 patients have been retrospectively analized in a five years period from August 2001 to August 2006. Age 60.9 years, 47.3% males, 11.84% DBT. AV fistulas: 59.2%, prothesis 27%, permanent catheter 13%. Weigth: 60.05 +/- 10.5Kg, BMI: 23 +/- 3.4 Kg/m2, height 156 +/-33 cm. Patients dialized 4 hs. three times a week, Qb/Qd 339 ml/min, with a PS 1.4 to 1.8 m2. Hemodialysis vintage: 6.9 +/- 6.1 years. Statistics: Stata 8.0. Adequacy formula according to Daugirdas with pre/post urea and slow flow procedure. The results obtained were: Kt/Vsp:1.51 +/- 0.27, Kt/Ve: 1.31 +/- 0.20 and URR %: 70.20% +/- 6.18. It means that using G batch system it is possible to obtain the dialysis doses recommended by K-DOQI 2006 and EBPG 2007 guidelines due to the technical quality of the equipment and the possibility of tailoring an individual treatment for each patient.